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Current human evidence from large-scale studies has not established a clear or direct link between GLP-1 medications and thyroid cancer in humans
These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
Current Weight Potential loss Calculator based on 20% average weight loss in 1 year with GLP-1 medication
& Hirsch, J
Common side effects include nausea or vomiting, constipation, bloating, diarrhea, and low energy
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