The EGFR/ErbB3 pathway acts as a compensatory survival mechanism upon c-Met inhibition in human c-Met+ hepatocellular carcinoma
10.1056/NEJM200011163432007 N
Research by Te-Sheng Chang found the lowest levels of reduced glutathione to be associated with eumelanin-type pigmentation, whereas the highest ones were associated with pheomelanin
Therefore, it seems to be of utmost importance to develop strategies and interventions that interfere with the aging process, prevent or at least mitigate age-associated diseases, and support healthy aging patterns, not only to elongate the lifespan but also to increase the healthspan - the phase of life spent in health, active, and in absent of chronic diseases (Seals et al., 2016)
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