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Acupoint stimulation modulates Glu and its receptors, inhibiting the ascending excitatory pathway by downregulating N -methyl-d-aspartate receptor type 2B and preventing -amino-3-hydroxy-5-methyl-4-isoxazole-propionicacid receptor phosphorylation, thus promoting the recovery of glutamate transporters to clear excessive Glu, thereby contributing to analgesic effects [174, 175]

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Note: Mounjaro , Victoza , Rybelsus , and Ozempic are not FDA-approved to treat obesity or for weight loss

p = 0.005 for 5.0 mg)