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Gene 1997, 192, 271281

In addition, various other nanoparticles have also been shown to improve the immunosuppressive tumor microenvironment by reducing MDSCs infiltration or decreasing MDSCs activity, such as high-density lipoprotein-like nanoparticles (HDL-NP) can specifically target the high-affinity receptor B-1 scavenger receptor (SCARB1) of spherical high-density lipoprotein (HDL) expressed by MDSCs thereby inhibiting MDSCs activity and enhancing the immune response to cancer and significantly inhibiting tumor growth (131)

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It has been shown to upregulate key growth factors such as Vascular Endothelial Growth Factor (VEGF), Transforming Growth Factor-beta (TGF-), and Fibroblast Growth Factor (FGF)

Serious symptoms such as allergic reactions or irregular heartbeat require immediate care