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The medicine is the hub of drugs

Yang L, Li W, Ding X, Zhao Y, Qian X, Shang L

Talsania, T

In April 2020, a new systemic inflammatory syndrome was first described in the paediatric population with features that overlapped those of Kawasaki disease, toxic shock syndrome and macrophage activation syndrome.1 An association with SARS-CoV-2 was rapidly established, as most affected patients tested positive for the virus and/or had clinical manifestations compatible with COVID-19 26 weeks prior to onset

The PDB 8OR0 (structure of a Hs Cullin-1 complex) superimposed onto the Hs Cullin-2 (chain E) of PDB 8RX0 (C RMSD 1.224 ) was used as a reference to position At ASK1 on the modelled At CUL1