It also reduces leukocyte infiltration and oxidative stress markers following injury
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If someone is insulin resistant, has sleep apnea risk, edema tendencies, or a cancer history, you dont treat this like a casual supplement decision
Monitor your overall health so that treatment stays appropriate and B12 is not masking another issue such as folate deficiency
Supplement Wisely Consider these nutrients to support methylation: Methyl-B12 and methyl-folate TMG, NAC, riboflavin Curcumin, fish oil, Vitamins C, D, E Probiotics Note: Those with double homozygous MTHFR mutations should use low doses and avoid niacin (B3), which can slow methylation