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Study selection The criteria for including studies in this meta-analysis were as follows: (1) (i) randomized controlled trials (RCTs) comparing different AOMs with placebo, including glucagon-like peptide 1 receptor agonist (GLP-1 RA), dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 RAs, GLP-1 and glucagon receptor (GCGR) dual-agonist, orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and bimagrumab

The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste, stability, and safety

Propionyl-L-Carnitine - This form is best used to improve blood flow in people with high blood pressure or related health problems

Available at: Gorgojo-Martnez JJ, Mezquita-Raya P, Carretero-Gmez J, et al

Both are MHRA-approved, supported by large Phase 3 clinical trials, and available on prescription in the UK