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BPC-157 is derived from gastric juice proteins and has extensive preclinical data showing gastroprotective effects, ulcer healing, and intestinal barrier repair

Consistent with the broad action of the incretins in the brain and the periphery, the receptors for GIP and GLP-1 receptors show widespread distribution that includes also hypothalamic and hindbrain regions implicated in regulation of body weight and food intake [52,53,54,55]