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Some evidence suggests semaglutide may have slightly higher discontinuation rates due to GI symptoms compared to some other GLP-1 agonists, though this varies by dose and individual factors

1988;55:98152 Available from: Loscalzo J

Mitochondrial failure is an age-related phenomenon that increases intracellular ROS and causes oxidative stress (Venkataraman et al., 2013)

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