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Studies often focus on receptor-mediated signaling dynamics and their potential association with cellular metabolic regulation, protein turnover processes, and neuroendocrine feedback mechanisms, as described in cell-based and animal research literature

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Furthermore, we found that both r-sFNDC5 and r-irisin promote fat oxidation in the liver, as indicated by decreased hepatic lipid accumulation and increased expression of fatty acid -oxidation genes (Figures 6I,J)