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Heat-enhanced linear growth may occur: (1) indirectly by increasing IGF-1 access/delivery to the growth plate with temperature-enhanced blood flow (endocrine actions), (2) directly by increasing IGF-1 activity within the growth plate (autocrine/paracrine actions) by temperature-enhanced expression of local regulators, or (3) a combination of both direct and indirect mechanisms

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Resveratrol rescues cadmium-induced mitochondrial injury by enhancing transcriptional regulation of PGC-1 and SOD2 via the Sirt3/FoxO3a pathway in TCMK-1 cells

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