However, the current studies on GA have not extensively investigated the role of unsaturated FAs in regulating the GA pathway, and the existing research remains incomplete
*Antioxidants alone will not be effective in the majority of melasma cases
Key validation metrics include pharmacokinetics/pharmacodynamics concordance (e.g., clearance rates, area under the curve [AUC], metabolite formation), toxicological sensitivity and specificity, and the recapitulation of clinical-grade disease phenotypes and drug responses
Limited ipamorelin-specific primary data
Imatinib targets the ATP-binding site of the BcrAbl tyrosine kinase and also inhibits the actions of other tyrosine kinases, including platelet-derived growth factor receptor-b, C-kit, and C-ABL [17]