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Description

Semaglutide used once weekly is bound to albumin in the blood allowing for a longer effect or once weekly dosing

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Retatrutidere is administered subcutaneously, with a half-life of 6 days, and therefore can be injected weekly [2]

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The TRIUMPH-1 trial showed 24% body weight reduction at 12mg over 48 weeks a number that put the entire GLP-1 space on notice

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Figure 2 Pharmacokinetics The pharmacokinetics in healthy volunteers and patients with T2D are comparable (57)

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Obesity: a chronic relapsing progressive disease process

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