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Results obtained in rats castrated before puberty (3 weeks of age) were taken as supporting this hypothesis, since the penile AR concentration remained at immature levels at 7 and 13 weeks after castration, but decreased to the respective age levels if DHT was administered immediately after castration.2 However, it should be noted that the total penile AR content in the castrated animal reaching adulthood remained as low as in the adult animal because the penis grew very little in that period

The plasma stability of GLP-1MK-801 was optimized through incorporation of different cysteine homologues to the C terminus of the peptide to facilitate disulfide conjugation to the linker (Extended Data Fig

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2009 Sep;139(9):1744-50

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