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In the current study, we first show in a large multicenter cohort of primary malignant peripheral nerve sheath tumors and second in a series of primary and metastatic melanomas that complete loss of H3K27 trimethylation is not a reliable marker to distinguish malignant peripheral nerve sheath tumor from melanoma

Most of all significantly downregulated proteins with an average fold change of less than 0.5 were Complex I subunit proteins (NADH dehydrogenase) (Fig

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