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Description

2.2 GIPR agonism serves to reduce GLP-1R mediated GI AEs in the clinic Treatment with GLP-1R agonists can drive nausea, diarrhea, vomiting, and constipation, which often results in discontinuation of treatment (6-10% of patients) or reduction in dose (~15% of patients) (63)

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After treatment, there were significant improvements in insulin sensitivity, testosterone levels, and markers of inflammation

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Some people attempt this, but its a suboptimal strategy

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Pediatr Cardiol 41(7):13911401

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