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Studies show small reductions in body weight, usually a few pounds over two to three months, in people whose weight gain is tied to chronic stress

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A summary of findings from previous docking studies of these prominent DPP-4 inhibitors (87) is illustrated in Figure 2B

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Although a number of studies identifying a key role for metformin in the gut were undertaken many years ago, more recent studies have focused on metformin action in the liver, where it undoubtedly exerts a glucose-lowering effect