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Research shows that GLP-1 medications slow gastric emptying and reduce nutrient absorption time in the small intestine, potentially lowering B12 levels by 10-15% over six to twelve months

This system-level approach enables combinatorial and rational drug designing and characterization of new master regulators for precision medicine

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So a definition such as the one above can be unrolled into several different linear sequences of KOs, each of which we consider to be a possible path through the module

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