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Meta-analysis Meta-analysis was performed using the R statistical program, R version 4.4.2 (The R Foundation for Statistical Computing, Wirtschaftsuniversitt Wien, Vienna, Austria) (Sterne et al., 2016

gently swirl to dissolve (do not shake vigorously) [2]

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Researchers who already use vial presentations may also find the pen format beneficial when reducing preparation time without changing the underlying research material

These factors motivate transcriptomic and proteomic profiling to detect unanticipated pathway activation, coupled with dose-window optimization to balance metabolic efficacy with system-level perturbations