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Blood tests to evaluate iron status, vitamin levels, kidney function, and thyroid function are commonly performed when investigating RLS

[DOI] [PMC free article] [PubMed] [Google Scholar] Tramutola A, Triplett JC, Di Domenico F, Niedowicz DM, Murphy MP, Coccia R, Perluigi M, Butterfield DA

Your provider should rule out medication adherence issues, medication interactions, stress-related changes, or hormonal factors before adjusting

For a comprehensive list of clinical warnings, the official documentation on Semaglutide side effects provides a detailed breakdown of medical precautions that every patient should review

In most cases, you may be able to start your new medication on your regular dosing day, 1 week after your last dose of the old medication