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Watch-outs to know: The FDA has flagged Semax as a peptide that might trigger an unwanted immune response, and it has raised concerns about impurity and lack of safety data in humans
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For example, intradiscal injection of bone morphogenetic protein-2 (BMP-2) induced degenerative changes [92] and weekly intradiscal treatment with growth and differentiation factor-5 (GDF-5) or insulin-like growth factor-1 (IGF-1) resulted in inflammatory reactions in the adjacent vertebrae and connective tissue infiltrates in the NP, causing the IVD to collapse [93]
To address this knowledge gap, the Jander lab has established Erysimum cheiranthoides (wormseed wallflower) as a model system for studying cardenolide biosynthesis
Magnesium in chronic kidney disease Stages 3 and 4 and in dialysis patients
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