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Mice exposed to chronic unpredictable mild stress (CUMS) for 6 weeks showed increased hypothalamic corticotropin-releasing hormone concentrations, elevated corticosterone levels and increased blood ammonia, which corresponded with anxiety-like behaviors, demonstrating HPA axis involvement in anxiety pathogenesis (Jia et al., 2024)

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Piezo1 was verified to be a key mediator of ferroptosis in TMC

CJC-1295 and Ipamorelin | Synergistic Effects There is strong research interest in the simultaneous application of GHRH analogs like CJC-1295 and ghrelin receptor agonists like ipamorelin