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The dual ESI ionization source settings were as follows: capillary voltage was 4.5 kV, nozzle voltage 1500 V, N2 pressure in the nebulized was 21 psi and the N2 flow rate and temperature as sheath gas was 11 Lmin 1 and 379 C, respectively

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Overexpression of MicroRNA-126 (miR-126) mitigates oxygen-glucose deprivation/reperfusion injury by reducing oxidative stress and inflammation through the activation of the SIRT1/NRF2 signaling pathway in human umbilical vein endothelial cells [75]