Specific to cardiovascular-related death, ELIXA and SUSTAIN-6 trials showed similar performance relative to the placebo [ HR = 0.98 (95% CI 0.781.22) and HR = 0.98 (95% CI 0.651.48), respectively]
The net cardiac benefit of weight loss typically outweighs arrhythmia risk for most patients, but individualized assessment is essential

What Youll Learn: What GLP-1s (Ozempic, Wegovy, Mounjaro, etc.) are, how they work, and what the current evidence shows The potential benefits and risks - medical, psychological, and social Questions of access, equity, stigma, and the cultural narratives surrounding weight What we know (and dont yet know) about the long-term outlook and what comes after GLP-1s How to make or support informed, autonomous decisions about treatment options Whats Included in This Digital Bundle: 2.5-hours video recording presentation slides Printable note-taking materials Private access to a dedicated course page Lifetime access return anytime, learn at your own pace Certificate of Attendance (issued after feedback form submission) Who Its For: This course is designed for anyone interested in understanding GLP-1s from individuals thinking about starting the journey, to those supporting loved ones, to professionals in health and wellbeing fields
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Prior pancreatitis, gallbladder disease, kidney problems, diabetic retinopathy, significant gastrointestinal symptoms, and use of insulin or sulfonylureas may require closer risk assessment rather than automatic exclusion