Indeed, their results showed slow motor function, measured by finger tapping speed, and anhedonia, the inability to feel pleasure and a common characteristic of depression, coincided with high levels of glutamate and myo-inositol in the basal ganglia
Marker genes were identified using FindAllMarkers R package focusing on genes expressed by more than 10% of cells within a cluster and with a log fold change greater than 0.26
Yazdani A, Lenz HJ, Pillonetto G, Mendez-Giraldez R, Yazdani A, Sanof H, Hadi R, Samiei E, Venook AP, Ratain MJ, Rashid N, Vincent BG, Qu X, Wen Y, Kosorok M, Symmans WF, JPYC S, Lee MS, Kopetz S , Nixon AB, Bertagnolli MM, Perou CM, Innocenti F
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Cognitive and memory function improvement