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Retatrutides 24.2% weight loss result comes from a 338-person Phase 2 trial with a relatively homogeneous population it cannot be directly compared to Tirzepatides 2,539-person Phase 3 SURMOUNT-1 data without acknowledging this statistical limitation

Both are convenient once-weekly subcutaneous injections, making them flexible and manageable for long-term use

Typical symptoms inclue: Burps with a distinctive rotten egg or sulphur smell Unpleasant taste in the mouth Frequent belching Possible accompanying bloating or abdominal discomfort May be worse after consuming certain foods Often occurs alongside other digestive symptoms How Common Are Sulphur Burps with GLP-1 Medicines

The researchers found that among adults who were overweight or obese who completed the 20-week run-in period with subcutaneous semaglutide, maintaining treatment with semaglutide resulted in continued weight loss over the following 48 weeks compared to switching to placebo

Currently, no dietary supplement patch has been approved by the FDA for weight loss or to manage obesity