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Clinical data now show improvements in heart failure with preserved ejection fraction, slowing of chronic kidney disease progression, resolution of metabolic dysfunction-associated steatohepatitis (MASH), and dramatic reductions up to 64% in sleep apnea severity
So, weight is not just weight
It often begins with subtle symptoms like excessive thirst, polyuria, and fatigue- but conceals a complex pathophysiological network ( + CD11c + myeloid cells and CD3 + T cells, and cytokines such as interleukin-1 (IL-1), tumor necrosis factor- (TNF-), and interleukin-6 (IL-6) ( Infectionsboth acute and chronicare increasingly recognized as modulators of this architecture