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In SUSTAIN-2, at week 56, a weight loss of 4.3 kg with semaglutide 0.5 mg and 6.1 kg with semaglutide 1.0 mg, and 1.9 kg with sitagliptin 100 mg was achieved (ETD, -2.35 kg with semaglutide 0.5 mg and -4.20 kg with semaglutide 1.0 mg vs

When semaglutide activates these receptors, it enhances feelings of fullness and reduces hunger signals

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