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JNK, monitored by puc-lacZ 65 , was activated when Dpp signalling was inhibited by expressing its inhibitor dad (Fig

It is commonly investigated in preclinical research models relating to peptide signalling pathways, receptor-mediated communication mechanisms, and endocrine-associated biological processes

As the primary source of reducing equivalents, NADPH is primarily produced by glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase in the pentose phosphate pathway (PPP)