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Studies use the combination to model pharmacological pulsatile GH secretion, examining pulse amplitude, duration, and inter-pulse interval providing a research tool for studying the consequences of pulsatile versus tonic GH release profiles on downstream IGF-1 production and GH target tissue responses

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In bone defects, application of P-15-containing bone substitutes increased the rate of bone growth compared to the defects left empty or filled with bone substitute alone [120, 121, 123, 124, 132, 138]