In addition to PDHC and OGDH(L)C, this action of thiamine is mediated by two other ThDP-dependent multienzyme complexes, i.e., those of branched chain 2-oxo acid dehydrogenase (BCODH) and OADH, functioning in the pathways of degradation of branched-chain -amino acids, and lysine and tryptophan, respectively (Figure 1)
These examples collectively highlight the pervasive, yet often overlooked, presence of hormetic effects within the food we consume, emphasizing the need for a nuanced understanding of dose-response relationships in the context of food and health
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meningitidis (Exley et al., 2005), which metabolizes the lactate by at least three lactate dehydrogenases: two membrane-bound flavin mononucleotide-containing lactate dehydrogenases, LldD and LdhD, which catalyze the oxidation of L -lactate and D -lactate, respectively, and a soluble NAD + -dependent D -lactate dehydrogenase, LdhA (Erwin and Gotschlich, 1993, Erwin and Gotschlich, 1996
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