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demonstrated that iron overload triggers ferroptosis in MC3T3-E1 cells, a murine osteoblast cell line, and that this process is attenuated by ferroptosis inhibitors ( Figure 3 Osteocytes Osteocytes are terminally differentiated osteoblasts embedded within the bone matrix, and they are the most abundant cell type in mineralized bone, playing a central role in maintaining skeletal homeostasis (31, 32)

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The concentration of -glutamyl- S -allyl-L-cysteine in cells of these tissues is calculated to be approximately 38 M, when the content of water in tissues is estimated to be 90%

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