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PNS treatment restores renal function via attenuating the accumulation of injury mitochondria and cell apoptosis in TECs (Liang et al., 2017

Additionally, dedicated rat and monkey studies, which included detailed histopathology revealed no drug-related myocarditis, valvulopathy, or accelerated atherosclerosis

Tesamorelin causes transient increases in fasting glucose (mean +4.7 mg/dL) due to growth hormones insulin-antagonistic effects, though this typically resolves within 8 weeks of discontinuation

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