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John-Michael Gamble, PhD, Clinical Associate Professor at the University of Waterloo, Canada, discussed the origin and biological plausibility of the concern over suicide risk in people using GLP-1 receptor agonists, relevant scientific evidence and its limitations, and the implications for prescribers and their patients
In the broader GLP-1 receptor agonist literature, there is growing interest in the relationship between these medicines and hormonal or sexual health
Approved Injection Sites for GLP-1 Agonists The three approved injection sites for GLP-1 receptor agonists are the abdomen, thigh, and upper arm
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A comprehensive analysis of 43,365 individuals from two US healthcare databases indicated that GLP-1 RAs do not elevate the risk of pulmonary aspiration during upper gastrointestinal endoscopy in patients with T2DM when compared to SGLT-2 inhibitors, yielding a pooled risk ratio of 0.98 (95% CI, 0.73 to 1.31) among GLP-1 RA users
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