Normally, when you eat, the lower esophageal sphincter (LES)a muscle that acts as a valve between the esophagus and the stomachopens to let food in and then closes tightly to keep acid out
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We found that in hepatoma HepG2 cells, cystine (oxidized form of cysteine) activated mTORC1 and suppressed the ISR
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DOI: 10.3389/fendo.2024.1431292 [Google Scholar] Armstrong MJ, Gaunt P, Aithal GP, Barton D, Hull D, Parker R, et al