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Summary The popular weight-loss drug Ozempic and similar GLP-1 medications are revealing surprising side effects beyond slimming

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Nevertheless, the pooled analysis of 16 trials suggested improvements in the summary measure of patients' global functioning (assessed with the Clinical Global Impressions [CGI-I] scale) after 12 and 24 weeks of (but not after 52 weeks) of ALCAR treatment (1-3 g/day) and in cognitive performance (assessed with the Mini-Mental State Examination [MMSE] scale) after 24 weeks (but not at 12 or 52 weeks) (104)

Patients on selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants need closer monitoring if phentermine is used, as serotonin syndrome, though rare, is a medical emergency