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Coumarin , L-leucine , and 3-indolepropionic acid emerged as top-ranking features based on mean decrease in accuracy, indicating their relative importance as diet-responsive metabolites within this cohort

Proper dosing requires slow titration to 2.4mg weekly over 12-16 weeks to minimize nausea and GI side effects

In clinical practice, a GLP-1 maintenance dose usually involves: Using the lowest effective dose Holding a dose steady rather than escalating Prioritising weight stability over further loss Can You Stay on Mounjaro or Wegovy Long Term

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It also communicates with appetite-regulating centres in the brain, helping you feel satisfied after eating and reducing the urge to keep snacking