First of all, at 5-foot-1, my 30-ish extra pounds rendered me technically overweight by body mass index
Weight loss, especially when its rapid or sustained, is still a form of physical stress
The data is from a phase three clinical trial funded by Eli Lilly and included nearly 1,700 people with diabetes
Research suggests that berberine may: Improve insulin sensitivity Support healthy glucose metabolism Influence gut microbiota composition Enhance pathways involved in GLP-1 secretion Other ingredients that may support GLP-1 activity include: Prebiotic fibers like inulin Polyphenols from green tea Omega-3 fatty acids These nutrients work by supporting metabolic processes linked to increase GLP-1 naturally, rather than directly mimicking the hormone
Are uncomfortable with compounded medications: If you have concerns about using medications that haven't undergone FDA review as finished products, or you strongly prefer FDA-approved options for peace of mind, brand-name Wegovy or Zepbound (if you can access them affordably) would be more appropriate than compounded formulations