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Mechanisms of Ageing and Development

Photochem Photobiol 84(3):582592 Funding None

These begin with alterations in SCFA signaling and subsequently diverge into bile acid-mediated pathways that modulate farnesoid X receptor (FXR) and Takeda G-protein-coupled receptor 5 (TGR5) activity [19 136]

These effects are mediated through binding of calcitonin to a specific receptor (the calcitonin receptor or CTR) on the osteoclast (20), a specialized cell that resorbs bone, causing it to retract and cease bone resorption (21)