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The second is an adaptor protein called PYCARD, or apoptosis-associated speck-like protein containing a CARD (ASC), which contains a caspase activation and recruitment (CARD) domain

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In human oocytes, the MTOC is constituted by four proteins located at the kinetochore and spindle microtubules: centriole coiledcoil protein 110 (CCP110), cytoskeleton-associated protein 5 (CKAP5), DISC1, and transforming acidic coiledcoil 3 (TACC3)

This distinction shapes how each compound gets used in a research setting