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Proc Natl Acad Sci U S A 105:1506415069

Cryo-EM image processing For the At ASK1 Sh MAX2 Sh HTL7 At SMAX1 dataset, an overview of the data processing can be found in Supplementary Fig 2

2.4 Pull-Down 1) Prepare the Magnetic Beads as 2.1

DSIP-like material was found by RIA and immunohistochemistry in brain and by RIA in peripheral organs of the rat as well as in plasma of several mammals

The MTHFD2 enzyme is resistant to inhibition by NADH and so this reaction can contribute to significant mitochondrial NADH production under increased serine catabolism as well as during periods where the major NADH producing catabolic pathways are inhibited by increasing NADH levels