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Across 809 participants with a mean starting weight of 114.2 kg, CagriSema produced 23.0 per cent weight loss when all patients adhered to treatment, against 25.5 per cent for tirzepatide

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Questions remain but this is nonetheless very encouraging, says study co-author Dr

Compounded semaglutide and tirzepatide are not FDA-approved drugs and are explicitly excluded from coverage

In the book, Kessler acknowledges that you can't really separate those unpleasant feelings from the effective mechanism of the drugs themselves