(38830068) Recently, there has been a trend towards using higher maintenance doses, with 1.5 grams q12 being used initially for most patients in status epilepticus
FIGURE 1 Given the role of GLP-1 in glycaemic control, the anti-apoptotic, growth-stimulating and insulin secretion-promoting effects on pancreatic -cells, the ability to re-sensitize the cellular insulin-signaling, minor side effects, good tolerance by normoglycemic patients and the fact that GLP-1 does not desensitize, synthetic GLP-1R agonists have been on the market for decades to treat type 2 diabetes mellitus (T2DM) or, more recently, to improve weight loss (Drucker, 2018)
Such drip-off dynamics can lead to a flawed estimate of regional deposition
They may suggest an over-the-counter antihistamine or decide to adjust your treatment plan
Consider dose adjustment timing