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We also demonstrated that cARLA treatment improved the predictive value of a human stem cell derived co-culture BBB model not only for small molecule drugs but also for targeted nanoparticles [40]

Ultrafast excited-state dynamics and photolysis studies have revealed that a new channel for rapid nonradiative decay in base-o MeCbl is opened, which competes with bond dissociation

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Lipid peroxidation is a radical chain reaction that decreases polyunsaturated fatty acids, disturbing the normal fluidity and permeability of the cell membranes and leading to cellular edema, calcium and sodium ion overload, and cell lysis