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Another study in patients with cirrhosis also showed up to a three-fold elevation of short-chain acyl-carnitine and long-chain acyl-carnitine in the plasma compared to healthy volunteers [66], and this has been supported by others [62,67]

A retrospective observational study published in Clinical Nutrition found that nutritional deficiencies were diagnosed in 12.7% of patients within 6 months of starting GLP-1 receptor agonists, and that number climbed to 22.4% within 12 months

2) promotes mitochondrial synthesis, increases transcription factor a (TFAM), polymerase subunit gamma (POLG), and peroxisome proliferator-activated receptor gamma coactivator 1- (PGC1) levels

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With high potential returns and increasing competition, companies are strategically positioning themselves to lead this emerging market, highlighting the transformative impact these drugs are expected to have in the coming years