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333 It is reported that LRRK2 G2019S dopaminergic neurons exhibit a decreased NAD + pool and a reduced sirtuin deacetylase activity, correlating with elevated acetylation of sirtuin substrates p53, -tubulin and SOD2

Common exclusions include: Cosmetic or lifestyle medications Over-the-counter drugs (unless prescribed and approved in certain states) Fertility treatments Erectile dysfunction medications (with limited medical exceptions) Nonmedically necessary weight loss drugs Experimental or nonFDA-approved drugs In many cases, excluded medications may still be available through prior authorization if a doctor can demonstrate medical necessity