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Epithelial cells, the essential physical barrier between the body and the environment, are prone to damage and even death when exposed to pollutants or allergens, which subsequently promote downstream immune responses [19, 20]

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Microbial post-translation modification of protein (PTMP) is of great significance in inducing autoimmune diseases

10,11 Oxides of nitrogen present in cigarette smoke react with superoxide to form reactive peroxynitrite

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