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Although cigarette smoke increases the number of alveolar macrophages, paradoxically cigarette smoke also reduces clearance of apoptotic lung epithelial cells and neutrophils by macrophages

This was compared to just 2.4% weight loss in the placebo group

Regional trends and disparities in newer GLP1 receptor agonist initiation among real-world adult patients eligible for obesity treatment

This shift could improve the immune system ability to clear misplaced endometrial tissue rather than feeding it with inflammatory signals

In SURMOUNT-2 (Fras et al., NEJM 2023), participants with type 2 diabetes and obesity achieved mean weight reductions of 12.8% to 15.7% depending on dose