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There is a significant loss of rods by 5 weeks of age (P35), around the time when cone degeneration begins, making evaluation of cone function by photopic b-wave ERG a desirable output for protecting photoreceptor survival with benchmarks at P35, P50 and P65 [9]

However, due to the side effects reported when using the standard prophylactic medication (antiepileptic drugs, calcium channel inhibitors) [38,39] or abortive therapy, the discovery of substances with a more gentle effect and better tolerance is still required, i.e., causing less side effects [40]