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These changes are closely related to the mechanism of abnormal nerve signals and nerve damage in diabetic peripheral neuropathy

44 Under specific conditions, the demand for ALC may exceed the capacity to synthesize this essential micronutrient

Patients with low glutathione levels may experience: Chronic fatigue Weakness Headaches Dizziness Problems sleeping Frequent illnesses Dermatitis Difficulty concentrating Painful joints Mood instability or depression There are also many chronic health conditions which are associated with low glutathione levels: autoimmune disorders fibromyalgia heart disease skin disorders To add to this frustration of chronic health condition sufferers, many of the more conventional treatments and prescription medications used to treat these conditions can further deplete glutathione levels in the body

Glutathione degradation is carried by -glutamyltranspeptidase (Ggt) which helps in recycling of the constituent amino acids

1 (4), 18 (2019) A